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Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing

Owen Guy Orcid Logo, Anitha Devadoss Orcid Logo, Rhiannan Forsyth, Ryan Bigham, Hina Abbasi, Muhammad Ali, Zari Tehrani Orcid Logo, Yufei Liu, Owen. J. Guy

Biosensors, Volume: 9, Issue: 1, Start page: 16

Swansea University Authors: Owen Guy Orcid Logo, Anitha Devadoss Orcid Logo, Zari Tehrani Orcid Logo

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DOI (Published version): 10.3390/bios9010016

Abstract

Grafting thin polymer layers on graphene enables coupling target biomolecules to graphene surfaces, especially through amide and aldehyde linkages with carboxylic acid and primary amine derivatives, respectively. However, functionalizing monolayer graphene with thin polymer layers without affecting...

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Published in: Biosensors
ISSN: 2079-6374
Published: 2019
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URI: https://cronfa.swan.ac.uk/Record/cronfa48292
first_indexed 2019-01-19T05:00:13Z
last_indexed 2019-04-02T10:16:18Z
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spelling 2019-03-29T12:45:23.9167401 v2 48292 2019-01-18 Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing c7fa5949b8528e048c5b978005f66794 0000-0002-6449-4033 Owen Guy Owen Guy true false a01150750f1c8eccbfeebffdde3fe8a1 0000-0002-8052-1820 Anitha Devadoss Anitha Devadoss true false fd8e614b01086804c80fbafa6fa6aaf5 0000-0002-5069-7921 Zari Tehrani Zari Tehrani true false 2019-01-18 EAAS Grafting thin polymer layers on graphene enables coupling target biomolecules to graphene surfaces, especially through amide and aldehyde linkages with carboxylic acid and primary amine derivatives, respectively. However, functionalizing monolayer graphene with thin polymer layers without affecting their exceptional electrical properties remains challenging. Herein, we demonstrate the controlled modification of chemical vapor deposition (CVD) grown single layer graphene with ultrathin polymer 1,5-diaminonaphthalene (DAN) layers using the electropolymerization technique. It is observed that the controlled electropolymerization of DAN monomer offers continuous polymer layers with thickness ranging between 5–25 nm. The surface characteristics of pure and polymer modified graphene was examined. As anticipated, the number of surface amine groups increases with increases in the layer thickness. The effects of polymer thickness on the electron transfer rates were studied in detail and a simple route for the estimation of surface coverage of amine groups was demonstrated using the electrochemical analysis. The implications of grafting ultrathin polymer layers on graphene towards horseradish peroxidase (HRP) enzyme immobilization and enzymatic electrochemical sensing of H2O2 were discussed elaborately. Journal Article Biosensors 9 1 16 2079-6374 Graphene; enzyme immobilization; functional polymers; electropolymerization; bio electrochemistry; electrochemical sensing; glucose biosensor; biofunctionalization 18 1 2019 2019-01-18 10.3390/bios9010016 https://www.mdpi.com/2079-6374/9/1/16 COLLEGE NANME Engineering and Applied Sciences School COLLEGE CODE EAAS Swansea University 2019-03-29T12:45:23.9167401 2019-01-18T21:08:18.1029484 Faculty of Science and Engineering School of Engineering and Applied Sciences - Chemistry Owen Guy 0000-0002-6449-4033 1 Anitha Devadoss 0000-0002-8052-1820 2 Rhiannan Forsyth 3 Ryan Bigham 4 Hina Abbasi 5 Muhammad Ali 6 Zari Tehrani 0000-0002-5069-7921 7 Yufei Liu 8 Owen. J. Guy 9 0048292-04022019094629.pdf devadoss2019(2).pdf 2019-02-04T09:46:29.7900000 Output 6374991 application/pdf Version of Record true 2019-02-04T00:00:00.0000000 true eng
title Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing
spellingShingle Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing
Owen Guy
Anitha Devadoss
Zari Tehrani
title_short Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing
title_full Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing
title_fullStr Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing
title_full_unstemmed Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing
title_sort Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing
author_id_str_mv c7fa5949b8528e048c5b978005f66794
a01150750f1c8eccbfeebffdde3fe8a1
fd8e614b01086804c80fbafa6fa6aaf5
author_id_fullname_str_mv c7fa5949b8528e048c5b978005f66794_***_Owen Guy
a01150750f1c8eccbfeebffdde3fe8a1_***_Anitha Devadoss
fd8e614b01086804c80fbafa6fa6aaf5_***_Zari Tehrani
author Owen Guy
Anitha Devadoss
Zari Tehrani
author2 Owen Guy
Anitha Devadoss
Rhiannan Forsyth
Ryan Bigham
Hina Abbasi
Muhammad Ali
Zari Tehrani
Yufei Liu
Owen. J. Guy
format Journal article
container_title Biosensors
container_volume 9
container_issue 1
container_start_page 16
publishDate 2019
institution Swansea University
issn 2079-6374
doi_str_mv 10.3390/bios9010016
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Chemistry{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Chemistry
url https://www.mdpi.com/2079-6374/9/1/16
document_store_str 1
active_str 0
description Grafting thin polymer layers on graphene enables coupling target biomolecules to graphene surfaces, especially through amide and aldehyde linkages with carboxylic acid and primary amine derivatives, respectively. However, functionalizing monolayer graphene with thin polymer layers without affecting their exceptional electrical properties remains challenging. Herein, we demonstrate the controlled modification of chemical vapor deposition (CVD) grown single layer graphene with ultrathin polymer 1,5-diaminonaphthalene (DAN) layers using the electropolymerization technique. It is observed that the controlled electropolymerization of DAN monomer offers continuous polymer layers with thickness ranging between 5–25 nm. The surface characteristics of pure and polymer modified graphene was examined. As anticipated, the number of surface amine groups increases with increases in the layer thickness. The effects of polymer thickness on the electron transfer rates were studied in detail and a simple route for the estimation of surface coverage of amine groups was demonstrated using the electrochemical analysis. The implications of grafting ultrathin polymer layers on graphene towards horseradish peroxidase (HRP) enzyme immobilization and enzymatic electrochemical sensing of H2O2 were discussed elaborately.
published_date 2019-01-18T19:38:32Z
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