Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis

Rybak, Jeffrey M.; Dickens, C. Michael; Parker, Josie; Caudle, Kelly E.; Manigaba, Kayihura; Whaley, Sarah G.; Nishimoto, Andrew T.; Luna-Tapia, Arturo; Roy, Sujoy; Zhang, Qing; Barker, Katherine S.; Palmer, Glen E.; Sutter, Thomas R.; Homayouni, Ramin; Wiederhold, Nathan P.; Kelly, Steven; Rogers, P. David

doi:10.1128/aac.00651-17

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Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis

Jeffrey M. Rybak, C. Michael Dickens, Josie Parker, Kelly E. Caudle, Kayihura Manigaba, Sarah G. Whaley, Andrew T. Nishimoto, Arturo Luna-Tapia, Sujoy Roy, Qing Zhang, Katherine S. Barker, Glen E. Palmer, Thomas R. Sutter, Ramin Homayouni, Nathan P. Wiederhold, Steven Kelly

, P. David Rogers

Antimicrobial Agents and Chemotherapy, Volume: 61, Issue: 9, Start page: AAC.00651-17

Swansea University Authors: Josie Parker, Steven Kelly

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DOI (Published version): 10.1128/aac.00651-17

Published in:	Antimicrobial Agents and Chemotherapy
ISSN:	0066-4804 1098-6596
Published:	American Society for Microbiology 2017
Online Access:	Check full text
URI:	https://cronfa.swan.ac.uk/Record/cronfa34548
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first_indexed	2017-07-04T15:07:57Z
last_indexed	2021-10-27T02:52:29Z
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spelling	2021-10-26T16:34:31.0097324 v2 34548 2017-07-04 Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis e563ed4e1c7db8d1e131fb78a5f8d0d5 Josie Parker Josie Parker true false b17cebaf09b4d737b9378a3581e3de93 0000-0001-7991-5040 Steven Kelly Steven Kelly true false 2017-07-04 FGMHL Journal Article Antimicrobial Agents and Chemotherapy 61 9 AAC.00651-17 American Society for Microbiology 0066-4804 1098-6596 1 9 2017 2017-09-01 10.1128/aac.00651-17 http://dx.doi.org/10.1128/aac.00651-17 COLLEGE NANME Medicine, Health and Life Science - Faculty COLLEGE CODE FGMHL Swansea University 2021-10-26T16:34:31.0097324 2017-07-04T10:38:20.9336710 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Jeffrey M. Rybak 1 C. Michael Dickens 2 Josie Parker 3 Kelly E. Caudle 4 Kayihura Manigaba 5 Sarah G. Whaley 6 Andrew T. Nishimoto 7 Arturo Luna-Tapia 8 Sujoy Roy 9 Qing Zhang 10 Katherine S. Barker 11 Glen E. Palmer 12 Thomas R. Sutter 13 Ramin Homayouni 14 Nathan P. Wiederhold 15 Steven Kelly 0000-0001-7991-5040 16 P. David Rogers 17 0034548-04072017103844.pdf Antimicrob.AgentsChemother.-2017-Rybak-AAC.00651-17.pdf 2017-07-04T10:38:44.0230000 Output 1729188 application/pdf Accepted Manuscript true 2017-12-19T00:00:00.0000000 6 month embargo. true eng
title	Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis
spellingShingle	Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis Josie Parker Steven Kelly
title_short	Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis
title_full	Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis
title_fullStr	Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis
title_full_unstemmed	Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis
title_sort	Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis
author_id_str_mv	e563ed4e1c7db8d1e131fb78a5f8d0d5 b17cebaf09b4d737b9378a3581e3de93
author_id_fullname_str_mv	e563ed4e1c7db8d1e131fb78a5f8d0d5_*_Josie Parker b17cebaf09b4d737b9378a3581e3de93_*_Steven Kelly
author	Josie Parker Steven Kelly
author2	Jeffrey M. Rybak C. Michael Dickens Josie Parker Kelly E. Caudle Kayihura Manigaba Sarah G. Whaley Andrew T. Nishimoto Arturo Luna-Tapia Sujoy Roy Qing Zhang Katherine S. Barker Glen E. Palmer Thomas R. Sutter Ramin Homayouni Nathan P. Wiederhold Steven Kelly P. David Rogers
format	Journal article
container_title	Antimicrobial Agents and Chemotherapy
container_volume	61
container_issue	9
container_start_page	AAC.00651-17
publishDate	2017
institution	Swansea University
issn	0066-4804 1098-6596
doi_str_mv	10.1128/aac.00651-17
publisher	American Society for Microbiology
college_str	Faculty of Medicine, Health and Life Sciences
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hierarchy_top_title	Faculty of Medicine, Health and Life Sciences
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hierarchy_parent_title	Faculty of Medicine, Health and Life Sciences
department_str	Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
url	http://dx.doi.org/10.1128/aac.00651-17
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published_date	2017-09-01T03:42:52Z
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Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis

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