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Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions

Nadia C. Lara, Asad A. Haider, Jason C. Ho, Lon J. Wilson, Andrew Barron Orcid Logo, Steven A. Curley, Stuart J. Corr

Chemical Communications, Volume: 52, Issue: 85, Pages: 12630 - 12633

Swansea University Author: Andrew Barron Orcid Logo

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DOI (Published version): 10.1039/C6CC06573B

Abstract

For potential applications in nano-mediated radiofrequency cancer hyperthermia, the nanomaterial under investigation must increase the heating of any aqueous solution in which it is suspended when exposed to radiofrequency electric fields. This should also be true for a broad range of solution condu...

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Published in: Chemical Communications
ISSN: 1359-7345 1364-548X
Published: 2016
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URI: https://cronfa.swan.ac.uk/Record/cronfa30918
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first_indexed 2016-11-03T14:26:46Z
last_indexed 2020-06-25T12:42:03Z
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spelling 2020-06-25T11:53:16.0878678 v2 30918 2016-11-03 Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions 92e452f20936d688d36f91c78574241d 0000-0002-2018-8288 Andrew Barron Andrew Barron true false 2016-11-03 CHEG For potential applications in nano-mediated radiofrequency cancer hyperthermia, the nanomaterial under investigation must increase the heating of any aqueous solution in which it is suspended when exposed to radiofrequency electric fields. This should also be true for a broad range of solution conductivities, especially those that artificially mimic the ionic environment of biological systems. Herein we demonstrate enhanced heating of biologically relevant aqueous solutions using kosmotropes and a hexamalonoserinolamide fullerene. Journal Article Chemical Communications 52 85 12630 12633 1359-7345 1364-548X 31 12 2016 2016-12-31 10.1039/C6CC06573B This paper provides a route for cancer treatment without complex material or drugs - it shows that by the alteration of the permtivity of a solution by simple bio-safe molecules radio irradiation can be used for selective heating of tumors. This work is now moving towards animal studies. COLLEGE NANME Chemical Engineering COLLEGE CODE CHEG Swansea University 2020-06-25T11:53:16.0878678 2016-11-03T12:21:43.2755758 Faculty of Science and Engineering School of Engineering and Applied Sciences - Chemical Engineering Nadia C. Lara 1 Asad A. Haider 2 Jason C. Ho 3 Lon J. Wilson 4 Andrew Barron 0000-0002-2018-8288 5 Steven A. Curley 6 Stuart J. Corr 7 0030918-03112016134104.pdf lara2016.pdf 2016-11-03T13:41:04.3700000 Output 960989 application/pdf Accepted Manuscript true 2017-09-30T00:00:00.0000000 true
title Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions
spellingShingle Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions
Andrew Barron
title_short Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions
title_full Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions
title_fullStr Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions
title_full_unstemmed Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions
title_sort Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions
author_id_str_mv 92e452f20936d688d36f91c78574241d
author_id_fullname_str_mv 92e452f20936d688d36f91c78574241d_***_Andrew Barron
author Andrew Barron
author2 Nadia C. Lara
Asad A. Haider
Jason C. Ho
Lon J. Wilson
Andrew Barron
Steven A. Curley
Stuart J. Corr
format Journal article
container_title Chemical Communications
container_volume 52
container_issue 85
container_start_page 12630
publishDate 2016
institution Swansea University
issn 1359-7345
1364-548X
doi_str_mv 10.1039/C6CC06573B
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Chemical Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Chemical Engineering
document_store_str 1
active_str 0
description For potential applications in nano-mediated radiofrequency cancer hyperthermia, the nanomaterial under investigation must increase the heating of any aqueous solution in which it is suspended when exposed to radiofrequency electric fields. This should also be true for a broad range of solution conductivities, especially those that artificially mimic the ionic environment of biological systems. Herein we demonstrate enhanced heating of biologically relevant aqueous solutions using kosmotropes and a hexamalonoserinolamide fullerene.
published_date 2016-12-31T03:37:41Z
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score 11.013641

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