No Cover Image

Journal article 1909 views 242 downloads

The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme

Andrew Warrilow Orcid Logo, Josie Parker, Claire Price Orcid Logo, W. David Nes, Edward P. Garvey, William J. Hoekstra, Robert J. Schotzinger, Diane Kelly, Steven Kelly

Antimicrobial Agents and Chemotherapy, Volume: 60, Issue: 8, Pages: 4530 - 4538

Swansea University Authors: Andrew Warrilow Orcid Logo, Josie Parker, Claire Price Orcid Logo, Diane Kelly, Steven Kelly

DOI (Published version): 10.1128/AAC.00349-16

Published in: Antimicrobial Agents and Chemotherapy
Published: 2016
URI: https://cronfa.swan.ac.uk/Record/cronfa29154
first_indexed 2016-07-08T12:21:11Z
last_indexed 2020-07-20T12:45:36Z
id cronfa29154
recordtype SURis
fullrecord <?xml version="1.0"?><rfc1807><datestamp>2020-07-20T10:02:18.6746776</datestamp><bib-version>v2</bib-version><id>29154</id><entry>2016-07-08</entry><title>The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme</title><swanseaauthors><author><sid>f066e233e8d0136c9f547b86fa43747f</sid><ORCID>0000-0003-0183-8334</ORCID><firstname>Andrew</firstname><surname>Warrilow</surname><name>Andrew Warrilow</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>e563ed4e1c7db8d1e131fb78a5f8d0d5</sid><firstname>Josie</firstname><surname>Parker</surname><name>Josie Parker</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>9a4e4dfa37f4318c6fa67933d4fc9a17</sid><ORCID>0000-0002-6045-4835</ORCID><firstname>Claire</firstname><surname>Price</surname><name>Claire Price</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>5ccf81e5d5beedf32ef8d7c3d7ac6c8c</sid><firstname>Diane</firstname><surname>Kelly</surname><name>Diane Kelly</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>b17cebaf09b4d737b9378a3581e3de93</sid><firstname>Steven</firstname><surname>Kelly</surname><name>Steven Kelly</name><active>true</active><ethesisStudent>false</ethesisStudent></author></swanseaauthors><date>2016-07-08</date><deptcode>MEDS</deptcode><abstract/><type>Journal Article</type><journal>Antimicrobial Agents and Chemotherapy</journal><volume>60</volume><journalNumber>8</journalNumber><paginationStart>4530</paginationStart><paginationEnd>4538</paginationEnd><publisher/><keywords/><publishedDay>1</publishedDay><publishedMonth>8</publishedMonth><publishedYear>2016</publishedYear><publishedDate>2016-08-01</publishedDate><doi>10.1128/AAC.00349-16</doi><url/><notes/><college>COLLEGE NANME</college><department>Medical School</department><CollegeCode>COLLEGE CODE</CollegeCode><DepartmentCode>MEDS</DepartmentCode><institution>Swansea University</institution><apcterm/><lastEdited>2020-07-20T10:02:18.6746776</lastEdited><Created>2016-07-08T08:29:47.4346544</Created><path><level id="1">Faculty of Medicine, Health and Life Sciences</level><level id="2">Swansea University Medical School - Medicine</level></path><authors><author><firstname>Andrew</firstname><surname>Warrilow</surname><orcid>0000-0003-0183-8334</orcid><order>1</order></author><author><firstname>Josie</firstname><surname>Parker</surname><order>2</order></author><author><firstname>Claire</firstname><surname>Price</surname><orcid>0000-0002-6045-4835</orcid><order>3</order></author><author><firstname>W. David</firstname><surname>Nes</surname><order>4</order></author><author><firstname>Edward P.</firstname><surname>Garvey</surname><order>5</order></author><author><firstname>William J.</firstname><surname>Hoekstra</surname><order>6</order></author><author><firstname>Robert J.</firstname><surname>Schotzinger</surname><order>7</order></author><author><firstname>Diane</firstname><surname>Kelly</surname><order>8</order></author><author><firstname>Steven</firstname><surname>Kelly</surname><order>9</order></author></authors><documents><document><filename>0029154-16082017120446.pdf</filename><originalFilename>Viamet_VT1129_Crypto_paper_Open_Access_May2016A.pdf</originalFilename><uploaded>2017-08-16T12:04:46.5370000</uploaded><type>Output</type><contentLength>658841</contentLength><contentType>application/pdf</contentType><version>Accepted Manuscript</version><cronfaStatus>true</cronfaStatus><embargoDate>2017-08-16T00:00:00.0000000</embargoDate><copyrightCorrect>true</copyrightCorrect><language>eng</language></document></documents><OutputDurs/></rfc1807>
spelling 2020-07-20T10:02:18.6746776 v2 29154 2016-07-08 The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme f066e233e8d0136c9f547b86fa43747f 0000-0003-0183-8334 Andrew Warrilow Andrew Warrilow true false e563ed4e1c7db8d1e131fb78a5f8d0d5 Josie Parker Josie Parker true false 9a4e4dfa37f4318c6fa67933d4fc9a17 0000-0002-6045-4835 Claire Price Claire Price true false 5ccf81e5d5beedf32ef8d7c3d7ac6c8c Diane Kelly Diane Kelly true false b17cebaf09b4d737b9378a3581e3de93 Steven Kelly Steven Kelly true false 2016-07-08 MEDS Journal Article Antimicrobial Agents and Chemotherapy 60 8 4530 4538 1 8 2016 2016-08-01 10.1128/AAC.00349-16 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University 2020-07-20T10:02:18.6746776 2016-07-08T08:29:47.4346544 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Andrew Warrilow 0000-0003-0183-8334 1 Josie Parker 2 Claire Price 0000-0002-6045-4835 3 W. David Nes 4 Edward P. Garvey 5 William J. Hoekstra 6 Robert J. Schotzinger 7 Diane Kelly 8 Steven Kelly 9 0029154-16082017120446.pdf Viamet_VT1129_Crypto_paper_Open_Access_May2016A.pdf 2017-08-16T12:04:46.5370000 Output 658841 application/pdf Accepted Manuscript true 2017-08-16T00:00:00.0000000 true eng
title The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme
spellingShingle The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme
Andrew Warrilow
Josie Parker
Claire Price
Diane Kelly
Steven Kelly
title_short The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme
title_full The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme
title_fullStr The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme
title_full_unstemmed The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme
title_sort The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme
author_id_str_mv f066e233e8d0136c9f547b86fa43747f
e563ed4e1c7db8d1e131fb78a5f8d0d5
9a4e4dfa37f4318c6fa67933d4fc9a17
5ccf81e5d5beedf32ef8d7c3d7ac6c8c
b17cebaf09b4d737b9378a3581e3de93
author_id_fullname_str_mv f066e233e8d0136c9f547b86fa43747f_***_Andrew Warrilow
e563ed4e1c7db8d1e131fb78a5f8d0d5_***_Josie Parker
9a4e4dfa37f4318c6fa67933d4fc9a17_***_Claire Price
5ccf81e5d5beedf32ef8d7c3d7ac6c8c_***_Diane Kelly
b17cebaf09b4d737b9378a3581e3de93_***_Steven Kelly
author Andrew Warrilow
Josie Parker
Claire Price
Diane Kelly
Steven Kelly
author2 Andrew Warrilow
Josie Parker
Claire Price
W. David Nes
Edward P. Garvey
William J. Hoekstra
Robert J. Schotzinger
Diane Kelly
Steven Kelly
format Journal article
container_title Antimicrobial Agents and Chemotherapy
container_volume 60
container_issue 8
container_start_page 4530
publishDate 2016
institution Swansea University
doi_str_mv 10.1128/AAC.00349-16
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 1
active_str 0
published_date 2016-08-01T03:56:55Z
_version_ 1851092124006612992
score 11.089572

Similar Items