Journal article 887 views
Probing cell surface interactions using atomic force microscope cantilevers functionalized for quantum dot-enabled Förster resonance energy transfer
Zhe Sun,
Ameet Juriani,
Gerald A Meininger,
Kenith Meissner
Journal of Biomedical Optics, Volume: 14, Issue: 4, Pages: 040502-1 - 040502-3
Swansea University Author: Kenith Meissner
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DOI (Published version): 10.1117/1.3174429
Abstract
Probing cell surface interactions using atomic force microscope cantilevers functionalized for quantum dot-enabled Förster resonance energy transfer
| Published in: | Journal of Biomedical Optics |
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| ISSN: | 1083-3668 |
| Published: |
2009
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| Online Access: |
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa16243 |
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| Item Description: |
This paper reports a method for cell surface profiling using near-field optical techniques coupled at the tip of an atomic force microscope (AFM). The technique couples Förster resonance energy transfer with microsphere AFM-based cell force measurements for combined biochemical/force profiling of focal adhesions in vascular smooth muscle cells. This work is focused on the study of cardiovascular disease. Combined with an earlier group paper (Pang et al., 2008), the work resulted in an NSF Interdisciplinary Research grant to develop cell surface profiling techniques. This work has led to numerous presentations and an invited talk at Microcirculation 2011 – Joint Meeting of the ESM and GfMVB. |
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| College: |
Faculty of Science and Engineering |
| Issue: |
4 |
| Start Page: |
040502-1 |
| End Page: |
040502-3 |