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Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors

Sarah C Ritter, Mark A Milanick, Kenith Meissner

Biomedical Optics Express, Volume: 2, Issue: 7, Pages: 2012 - 2021

Swansea University Author: Kenith Meissner

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DOI (Published version): 10.1364/BOE.2.002012

Published in: Biomedical Optics Express
ISSN: 2156-7085 2156-7085
Published: 2011
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URI: https://cronfa.swan.ac.uk/Record/cronfa16242
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first_indexed 2013-10-02T02:32:12Z
last_indexed 2018-02-09T04:48:50Z
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spelling 2016-08-17T13:57:48.0373486 v2 16242 2013-10-01 Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors 30fdfec0d8b19b59b57a818e054d4af3 Kenith Meissner Kenith Meissner true false 2013-10-01 FGSEN Journal Article Biomedical Optics Express 2 7 2012 2021 2156-7085 2156-7085 31 12 2011 2011-12-31 10.1364/BOE.2.002012 This paper presents the first use of functionalized red blood cells as a platform for sensing the extracellular environment. The general concept is to functionalize red blood cells with optical sensors that enable noninvasive optical measurements of blood analytes. The red blood cells are functionalized by diffusing optically active sensors through lysis pores into the cells. This paper provides proof of concept through detection of extracellular pH. The paper led directly to an NIH R21 grant with our collaborators, Prof. Milanick and Prof. Glass (University of Missouri). This has led to numerous presentations and an invited talk at PQE (January 2014). COLLEGE NANME Science and Engineering - Faculty COLLEGE CODE FGSEN Swansea University 2016-08-17T13:57:48.0373486 2013-10-01T20:27:23.0816679 Faculty of Science and Engineering School of Engineering and Applied Sciences - Uncategorised Sarah C Ritter 1 Mark A Milanick 2 Kenith Meissner 3
title Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors
spellingShingle Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors
Kenith Meissner
title_short Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors
title_full Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors
title_fullStr Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors
title_full_unstemmed Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors
title_sort Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors
author_id_str_mv 30fdfec0d8b19b59b57a818e054d4af3
author_id_fullname_str_mv 30fdfec0d8b19b59b57a818e054d4af3_***_Kenith Meissner
author Kenith Meissner
author2 Sarah C Ritter
Mark A Milanick
Kenith Meissner
format Journal article
container_title Biomedical Optics Express
container_volume 2
container_issue 7
container_start_page 2012
publishDate 2011
institution Swansea University
issn 2156-7085
2156-7085
doi_str_mv 10.1364/BOE.2.002012
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Uncategorised{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Uncategorised
document_store_str 0
active_str 0
published_date 2011-12-31T03:18:35Z
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score 11.013148

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