Journal article 1606 views 437 downloads
The MIT Domain of UBPY Constitutes a CHMP Binding and Endosomal Localization Signal Required for Efficient Epidermal Growth Factor Receptor Degradation
P. E Row,
H Liu,
S Hayes,
R Welchman,
P Charalabous,
K Hofmann,
M. J Clague,
C. M Sanderson,
S Urbe,
Paula Row
Journal of Biological Chemistry, Volume: 282, Issue: 42, Pages: 30929 - 30937
Swansea University Author: Paula Row
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DOI (Published version): 10.1074/jbc.M704009200
Abstract
The MIT Domain of UBPY Constitutes a CHMP Binding and Endosomal Localization Signal Required for Efficient Epidermal Growth Factor Receptor Degradation
Published in: | Journal of Biological Chemistry |
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ISSN: | 0021-9258 1083-351X |
Published: |
2007
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Online Access: |
Check full text
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URI: | https://cronfa.swan.ac.uk/Record/cronfa1511 |
Item Description: |
Row cloned the GFP-UBPY constructs, taught Hayes how to do the co-immunoprecipitation experiment, designed and performed the experiment that showed that UBPY lacking the MIT domain was functionally inactive, performed the experiment to localise UBPY delta MIT, and contributed to writing the manuscript. |
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College: |
Faculty of Medicine, Health and Life Sciences |
Issue: |
42 |
Start Page: |
30929 |
End Page: |
30937 |