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More than a colour change: insect melanism, disease resistance and fecundity

I. M. Dubovskiy, M. M. A. Whitten, V. Y. Kryukov, O. N. Yaroslavtseva, E. V. Grizanova, C. Greig, K. Mukherjee, A. Vilcinskas, P. V. Mitkovets, V. V. Glupov, T. M. Butt, Miranda Walker (neeWhitten) Orcid Logo, Tariq Butt Orcid Logo, Carolyn Greig

Proceedings of the Royal Society B: Biological Sciences, Volume: 280, Issue: 1763, Pages: 20130584 - 20130584

Swansea University Authors: Miranda Walker (neeWhitten) Orcid Logo, Tariq Butt Orcid Logo, Carolyn Greig

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DOI (Published version): 10.1098/rspb.2013.0584

Abstract

A “dark morph” melanic strain of the Greater wax moth, Galleria mellonella, was studied for its atypical, heightened resistance to infection with the entomopathogenic fungus, Beauveria bassiana. We show that these insects exhibit multiple intraspecific immunity and physiological traits that distingu...

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Published in: Proceedings of the Royal Society B: Biological Sciences
ISSN: 0962-8452 1471-2954
Published: 2013
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URI: https://cronfa.swan.ac.uk/Record/cronfa14615
first_indexed 2013-07-23T12:12:32Z
last_indexed 2019-07-01T19:20:36Z
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We show that these insects exhibit multiple intraspecific immunity and physiological traits that distinguish them from a non-melanic, fungus-susceptible morph. The melanic and non-melanic morphs were geographic variants that had evolved different, independent, defence strategies. Melanic morphs exhibit a thickened cuticle, higher basal expression of immunity and stress-management related genes, higher numbers of circulating haemocytes, upregulated cuticle phenoloxidase activity concomitant with conidial invasion, and an enhanced capacity to encapsulate fungal particles. These insects prioritize specific augmentations to those front-line defences that are most likely to encounter invading pathogens or to sustain damage. Other immune responses that target late-stage infection, such as haemolymph lysozyme and phenoloxidase activities, do not contribute to fungal tolerance. The net effect is increased larval survival times, retarded cuticular fungal penetration and a lower propensity to develop haemolymph infections when challenged naturally (topically) and by injection. In the absence of fungal infection, however, the heavy defence investments made by melanic insects result in a lower biomass, decreased longevity and lower fecundity in comparison with their non-melanic counterparts. 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spelling 2019-07-01T16:11:55.1603462 v2 14615 2013-04-19 More than a colour change: insect melanism, disease resistance and fecundity 83389c57d000a704fae36fda87d7ca76 0000-0003-1930-5042 Miranda Walker (neeWhitten) Miranda Walker (neeWhitten) true false 85d1c2ddde272a1176e74978e25ebece 0000-0002-8789-9543 Tariq Butt Tariq Butt true false 7f95061328bd6726f7472ced9cb8d937 Carolyn Greig Carolyn Greig true false 2013-04-19 MEDS A “dark morph” melanic strain of the Greater wax moth, Galleria mellonella, was studied for its atypical, heightened resistance to infection with the entomopathogenic fungus, Beauveria bassiana. We show that these insects exhibit multiple intraspecific immunity and physiological traits that distinguish them from a non-melanic, fungus-susceptible morph. The melanic and non-melanic morphs were geographic variants that had evolved different, independent, defence strategies. Melanic morphs exhibit a thickened cuticle, higher basal expression of immunity and stress-management related genes, higher numbers of circulating haemocytes, upregulated cuticle phenoloxidase activity concomitant with conidial invasion, and an enhanced capacity to encapsulate fungal particles. These insects prioritize specific augmentations to those front-line defences that are most likely to encounter invading pathogens or to sustain damage. Other immune responses that target late-stage infection, such as haemolymph lysozyme and phenoloxidase activities, do not contribute to fungal tolerance. The net effect is increased larval survival times, retarded cuticular fungal penetration and a lower propensity to develop haemolymph infections when challenged naturally (topically) and by injection. In the absence of fungal infection, however, the heavy defence investments made by melanic insects result in a lower biomass, decreased longevity and lower fecundity in comparison with their non-melanic counterparts. Although melanism is clearly correlated with increased fungal resistance, the costly mechanisms enabling this protective trait constitute more than just a colour change. Journal Article Proceedings of the Royal Society B: Biological Sciences 280 1763 20130584 20130584 0962-8452 1471-2954 31 7 2013 2013-07-31 10.1098/rspb.2013.0584 Accepted in principle for Publication; no doi assigned yet; currently in final proof stage for imminent publication. COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University 2019-07-01T16:11:55.1603462 2013-04-19T23:14:49.3379999 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine I. M. Dubovskiy 1 M. M. A. Whitten 2 V. Y. Kryukov 3 O. N. Yaroslavtseva 4 E. V. Grizanova 5 C. Greig 6 K. Mukherjee 7 A. Vilcinskas 8 P. V. Mitkovets 9 V. V. Glupov 10 T. M. Butt 11 Miranda Walker (neeWhitten) 0000-0003-1930-5042 12 Tariq Butt 0000-0002-8789-9543 13 Carolyn Greig 14
title More than a colour change: insect melanism, disease resistance and fecundity
spellingShingle More than a colour change: insect melanism, disease resistance and fecundity
Miranda Walker (neeWhitten)
Tariq Butt
Carolyn Greig
title_short More than a colour change: insect melanism, disease resistance and fecundity
title_full More than a colour change: insect melanism, disease resistance and fecundity
title_fullStr More than a colour change: insect melanism, disease resistance and fecundity
title_full_unstemmed More than a colour change: insect melanism, disease resistance and fecundity
title_sort More than a colour change: insect melanism, disease resistance and fecundity
author_id_str_mv 83389c57d000a704fae36fda87d7ca76
85d1c2ddde272a1176e74978e25ebece
7f95061328bd6726f7472ced9cb8d937
author_id_fullname_str_mv 83389c57d000a704fae36fda87d7ca76_***_Miranda Walker (neeWhitten)
85d1c2ddde272a1176e74978e25ebece_***_Tariq Butt
7f95061328bd6726f7472ced9cb8d937_***_Carolyn Greig
author Miranda Walker (neeWhitten)
Tariq Butt
Carolyn Greig
author2 I. M. Dubovskiy
M. M. A. Whitten
V. Y. Kryukov
O. N. Yaroslavtseva
E. V. Grizanova
C. Greig
K. Mukherjee
A. Vilcinskas
P. V. Mitkovets
V. V. Glupov
T. M. Butt
Miranda Walker (neeWhitten)
Tariq Butt
Carolyn Greig
format Journal article
container_title Proceedings of the Royal Society B: Biological Sciences
container_volume 280
container_issue 1763
container_start_page 20130584
publishDate 2013
institution Swansea University
issn 0962-8452
1471-2954
doi_str_mv 10.1098/rspb.2013.0584
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
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description A “dark morph” melanic strain of the Greater wax moth, Galleria mellonella, was studied for its atypical, heightened resistance to infection with the entomopathogenic fungus, Beauveria bassiana. We show that these insects exhibit multiple intraspecific immunity and physiological traits that distinguish them from a non-melanic, fungus-susceptible morph. The melanic and non-melanic morphs were geographic variants that had evolved different, independent, defence strategies. Melanic morphs exhibit a thickened cuticle, higher basal expression of immunity and stress-management related genes, higher numbers of circulating haemocytes, upregulated cuticle phenoloxidase activity concomitant with conidial invasion, and an enhanced capacity to encapsulate fungal particles. These insects prioritize specific augmentations to those front-line defences that are most likely to encounter invading pathogens or to sustain damage. Other immune responses that target late-stage infection, such as haemolymph lysozyme and phenoloxidase activities, do not contribute to fungal tolerance. The net effect is increased larval survival times, retarded cuticular fungal penetration and a lower propensity to develop haemolymph infections when challenged naturally (topically) and by injection. In the absence of fungal infection, however, the heavy defence investments made by melanic insects result in a lower biomass, decreased longevity and lower fecundity in comparison with their non-melanic counterparts. Although melanism is clearly correlated with increased fungal resistance, the costly mechanisms enabling this protective trait constitute more than just a colour change.
published_date 2013-07-31T18:26:57Z
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score 11.04748

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