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Implantable Electrochemical Biosensors – A Perspective

Sridhar Govindarajan, Bella B Manshian

Biomedical Nanosensors

Swansea University Author: Sridhar Govindarajan

Abstract

Implantable electrochemical sensors offer great potential for improving the quality of healthcare for patients with chronic diseases (such as diabetes) and in hospital critical care. This chapter will deal with biosensors designed for continuous, real-time monitoring of analytes in the human body. S...

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Published in: Biomedical Nanosensors
Published: Stanford Press 2012
URI: https://cronfa.swan.ac.uk/Record/cronfa13019
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spelling 2013-06-10T15:20:40.0773105 v2 13019 2012-10-09 Implantable Electrochemical Biosensors – A Perspective 1801789f07b9110521eb1e05363b66e9 Sridhar Govindarajan Sridhar Govindarajan true false 2012-10-09 Implantable electrochemical sensors offer great potential for improving the quality of healthcare for patients with chronic diseases (such as diabetes) and in hospital critical care. This chapter will deal with biosensors designed for continuous, real-time monitoring of analytes in the human body. Some of the recent developments and progress in the area of implantable electrochemical micro/nano biosensors have been highlighted. The focus of this work is on aspects requiring deliberation during the design of implantable biosensors such as size and power, performance factors and additional considerations such as sterilization and in vivo calibration. Particularly, issues such as selectivity, biofouling, power supply, sterility and in vivo calibration appear to preclude the use of biosensors as a means for routine clinical diagnosis and bedside monitoring. Despite advancements in the fields of micro/nano technology, biomaterials and bioelectrochemistry, and considerable effort to overcome these obstacles, continuous, real-time, reliable and long term monitoring of analytes in vivo still continues to be a challenge. Book chapter Biomedical Nanosensors Stanford Press Nanobiosensors, Implatable sensors, biocompatibility, sterility, power supply, toxicity 20 12 2012 2012-12-20 In Press. To be available end of 2012. COLLEGE NANME COLLEGE CODE Swansea University 2013-06-10T15:20:40.0773105 2012-10-09T11:58:27.8651943 Faculty of Science and Engineering School of Engineering and Applied Sciences - Uncategorised Sridhar Govindarajan 1 Bella B Manshian 2
title Implantable Electrochemical Biosensors – A Perspective
spellingShingle Implantable Electrochemical Biosensors – A Perspective
Sridhar Govindarajan
title_short Implantable Electrochemical Biosensors – A Perspective
title_full Implantable Electrochemical Biosensors – A Perspective
title_fullStr Implantable Electrochemical Biosensors – A Perspective
title_full_unstemmed Implantable Electrochemical Biosensors – A Perspective
title_sort Implantable Electrochemical Biosensors – A Perspective
author_id_str_mv 1801789f07b9110521eb1e05363b66e9
author_id_fullname_str_mv 1801789f07b9110521eb1e05363b66e9_***_Sridhar Govindarajan
author Sridhar Govindarajan
author2 Sridhar Govindarajan
Bella B Manshian
format Book chapter
container_title Biomedical Nanosensors
publishDate 2012
institution Swansea University
publisher Stanford Press
college_str Faculty of Science and Engineering
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hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Uncategorised{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Uncategorised
document_store_str 0
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description Implantable electrochemical sensors offer great potential for improving the quality of healthcare for patients with chronic diseases (such as diabetes) and in hospital critical care. This chapter will deal with biosensors designed for continuous, real-time monitoring of analytes in the human body. Some of the recent developments and progress in the area of implantable electrochemical micro/nano biosensors have been highlighted. The focus of this work is on aspects requiring deliberation during the design of implantable biosensors such as size and power, performance factors and additional considerations such as sterilization and in vivo calibration. Particularly, issues such as selectivity, biofouling, power supply, sterility and in vivo calibration appear to preclude the use of biosensors as a means for routine clinical diagnosis and bedside monitoring. Despite advancements in the fields of micro/nano technology, biomaterials and bioelectrochemistry, and considerable effort to overcome these obstacles, continuous, real-time, reliable and long term monitoring of analytes in vivo still continues to be a challenge.
published_date 2012-12-20T03:14:55Z
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score 11.037056

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