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Detecting oxysterols in the human circulation

Ingemar Björkhem, Ulf Diczfalusy, Tomas Olsson, David W Russell, Jeffery G McDonald, Yuqin Wang Orcid Logo, William Griffiths Orcid Logo

Nature Immunology, Volume: 12, Issue: 7, Pages: 577 - 577

Swansea University Authors: Yuqin Wang Orcid Logo, William Griffiths Orcid Logo

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DOI (Published version): 10.1038/ni0711-577a

Abstract

Oxysterols are oxygenated metabolites of cholesterol. On the basis of in vitro experiments, oxysterols have been ascribed many regulatory roles in connection with inflammation, neurodegeneration and atherosclerosis. They are present in trace amounts in biological systems, and their analysis represen...

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Published in: Nature Immunology
ISSN: 1529-2908 1529-2916
Published: 2011
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa10759
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Abstract: Oxysterols are oxygenated metabolites of cholesterol. On the basis of in vitro experiments, oxysterols have been ascribed many regulatory roles in connection with inflammation, neurodegeneration and atherosclerosis. They are present in trace amounts in biological systems, and their analysis represents a challenging analytical problem.
College: Faculty of Medicine, Health and Life Sciences
Issue: 7
Start Page: 577
End Page: 577