Journal article 1252 views
Lipopolysaccharide Initiates Inflammation in Bovine Granulosa Cells via the TLR4 Pathway and Perturbs Oocyte Meiotic Progression in Vitro
Endocrinology, Volume: 152, Issue: 12, Pages: 5029 - 5040
Swansea University Authors: Martin Sheldon , John Bromfield
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DOI (Published version): 10.1210/en.2011-1124
Abstract
Uncovers the mechanism of how ovarian follicles can respond to bacterial infections at a distant site.Granulosa cells of ovarian follicles have innate immune capabilities.First report in any species of LPS toxin of Gram-negative bacteria causing direct damage to oocytes.
Published in: | Endocrinology |
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ISSN: | 0013-7227 |
Published: |
2011
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Online Access: |
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URI: | https://cronfa.swan.ac.uk/Record/cronfa10278 |
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Abstract: |
Uncovers the mechanism of how ovarian follicles can respond to bacterial infections at a distant site.Granulosa cells of ovarian follicles have innate immune capabilities.First report in any species of LPS toxin of Gram-negative bacteria causing direct damage to oocytes. |
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Item Description: |
Sheldon designed and led the research; did some of experiments; did analysis and wrote the paper with Dr Bromfield |
Keywords: |
Innate immunity; ovary; oocyte |
College: |
Faculty of Medicine, Health and Life Sciences |
Issue: |
12 |
Start Page: |
5029 |
End Page: |
5040 |